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Nurse Practitioner Jobs in Missouri

Showing 39 nurse practitioner opportunities in Missouri

38 in cities, 1 statewide

General Nurse Practitioner
Kansas City, Missouri
Centerpoint Medical Center
Full-time
Permanent
In-person

Description Specialization: Neurosurgery Job Summary: Centerpoint Medical Center is recruiting a neurosurgery advanced practice provider in lndependence, Missouri. Qualified Candidates: • ICU or Neuro ICU experience required • Position is full time with flexible 12 hour shifts • Inpatient and ER consults • This position does not include first assist responsibilities • Ability to obtain a Missouri licensure Incentive/Benefits Package: • Competitive salary commensurate with experience • Comprehensive benefits package including ...

General Nurse Practitioner
Belton, Missouri
Belton Regional Medical Center
Full-time
Permanent
In-person

Description Specialization: Family Medicine without OB Job Summary: Belton Regional Medical Center is seeking an outpatient only primary care Advanced Practice Provider to join a long established, busy practice in Belton, Missouri.   • Qualified Candidates: • Comfortable with a quick ramp up • Practice has three family medicine physicians, three advanced practice providers • Critical Lab Call Only • Board certified or board eligible family medicine • Eligible for Missouri licensure   • Incentive/Benefits Package: • Patients-fir...

General Nurse Practitioner
Kansas City, Missouri
Weatherby Healthcare
Full-time
Locum Tenens
In-person
$80-$105 per hour

Enjoy the locum tenens lifestyle knowing Weatherby is here to support you every step of the way. Call and speak to one of our consultants today for available dates and details. • 12-hour shifts -- days (7 am - 7 pm) and nights (7 pm - 7 am) • Must be able to work both day and night shifts • Level IV NICU facility • Expanding locum NNP team -- joining established locum coverage • NRP and ACLS certifications required • Board certification required • Health, vision, dental, and 401(k) retirement benefits offered • Competitive compensation •...

General Nurse Practitioner
Kansas City, Missouri
AAS Healthcare Staffing
Full-time
Permanent
In-person

Provide patient-centered primary care to residents in skilled nursing facilities across Kansas City, MO. Full-time position with flexible scheduling, no overnight or on-call duties. Work collaboratively with physicians, nursing staff, and interdisciplinary teams to deliver evidence-based care. Schedule and Responsibilities • Full-time; six-hour facility shifts. Rounds generally start between 7:00 a.m. and 10:00 a.m. • Average 15-20 patient visits per day. • Conduct daily rounds; evaluate and manage acute and chronic conditions. • ...

General Nurse Practitioner
Columbia, Missouri
AAS Healthcare Staffing
Full-time
Permanent
In-person

Provide patient-centered primary care to residents in skilled nursing facilities across Columbia, Missouri. Work collaboratively with physicians, nursing staff, and interdisciplinary teams to deliver evidence-based care in a part-time role with flexible scheduling and no call or overnight duties. Key responsibilities • Perform daily rounds and manage acute and chronic conditions • Assess patients, prescribe medications, and develop/update treatment plans • Coordinate care with facility staff, families, and interdisciplinary teams ...

General Nurse Practitioner
Maryville, Missouri
AAS Healthcare Staffing
Full-time
Permanent
In-person

We’re expanding a team that brings patient-focused primary care into skilled nursing facilities in Maryville, Missouri, and we’re looking for part-time providers who value collaboration, flexibility, and high-quality, evidence-based care. You’ll work alongside physicians and facility staff to manage both acute and chronic needs for residents - without overnight shifts or on-call responsibilities. What the role looks like • Part-time schedule with flexible hours: six-hour facility shifts, with rounds generally starting between 7:00 a....

General Nurse Practitioner
Poplar Bluff, Missouri
CompHealth
Full-time
Locum Tenens
In-person
$75-$121 per hour

Though your CompHealth recruiter will be your single point of contact, they are backed by dozens of specialized teams, giving them the ability to focus on the details that matter to you. That means we have specialized teams that do nothing but housing, travel arrangements, credentialing, licensing, and so much more. It is one more way we deliver what matters to you. • Shifts available: 7 am - 7 pm, 10 am - 10 pm, and 7 pm - 7 am • 24 patients per shift • Inpatient setting • Patients range from neonate to elderly • Certifications required...

General Nurse Practitioner
Kansas City, Missouri
Research Medical Center
Full-time
Permanent
In-person

Description Specialization: Internal Medicine Job Summary: Internal Medicine Associates of Kansas City is seeking an advanced practice provider for a full time opportunity: Qualified Candidates:  • Must have at least a year of experience in an Internal Medicine role • Ability to work 5 days a week/fulltime • Have an active Missouri license Incentives/Benefits Package: • In addition to unmatched potential for flexibility and career growth and a competitive salary with incentives, a comprehensive benefits program is available for f...

General Nurse Practitioner
Poplar Bluff, Missouri
Weatherby Healthcare
Full-time
Locum Tenens
In-person
$75-$121 per hour

Weatherby can help you build a custom career plan, with multiple positions available for you today. Call us for specific details on your future job today. • All shifts: 7 am - 7 pm, 10 am - 10 pm, 7 pm - 7 am • Full-time schedule -- must be willing to work all shifts • Emergency medicine NP role • Certifications required: NRP, PALS, ACLS, and BLS • Health, vision, dental, and 401(k) retirement benefits offered • Competitive compensation • Paid malpractice insurance • 24-hour access to your Weatherby Healthcare consultant and support team...

General Nurse Practitioner
St. Louis, Missouri
Pediatrix & Obstetrix
PRN
Permanent
In-person

Per Diem NNP Opportunity in St. Louis MO! • 24 hour in house coverage • 100-bed, Level-IV NICU • Average daily census of 90, with 1,500 admissions and more than 10,000 deliveries annually • Current APRN national specialty certification • Minimum of a master’s degree  • Minimum 1 year of experience • Active MO license or ability to obtainPediatrix does cover per diem staff travel expenses (round trip flight/rental car or mileage and lodging) for those who reside outside a commutable distance from the practice. This position is W-2. *Our...

General Nurse Practitioner
Kansas City, Missouri
Pediatrix & Obstetrix
PRN
Permanent
In-person

**Per Diem** Seeking (NNP) Neonatal Nurse Practitioners seeking additional shifts at our Kansas City, MO Practice! Apply Today! • The System Includes 3 locations: St Lukes Hospital of Kansas City, St Lukes East Lees Summit and St Lukes North. • 49-bed, Level-IIIB NICU, a 15-bed Level-IIIA NICU, as well as one Level-II NICU and well-baby coverage. • 24 Hour and 12 Hour Inhouse Shifts Available • Current APRN National Specialty Certification • Minimum of a Master’s Degree  • Minimum of 1 Years Experience • Active MO License or Compact Eli...

General Nurse Practitioner
St. Louis, Missouri
Pediatrix & Obstetrix
Full-time
Permanent
In-person

We are seeking a Neonatal Nurse Practitioner to join our progressive, growing neonatal practice at Mercy Children’s Hospital in St. Louis. MO. Our Team: • We have a team approach toward care in this 100-bed, Level-IV NICU • Average daily census of 90, with 1,500 admissions and more than 10,000 deliveries annually • Neonatologists and NNPs provide 24-hour, in-house care • We provide a challenging clinical environment including conventional and high-frequency (both HFJV and HFOV) ventilation, nitric oxide and whole body cooling • Our tea...

General Nurse Practitioner
Kansas City, Missouri
Pediatrix & Obstetrix
Full-time
Permanent
In-person

Neonatal Nurse Practitioner (NNP) Generous Sign-On Bonus | Tuition Reimbursement for New Graduates | Relocation Assistance Available Launch or advance your Neonatal Nurse Practitioner career with a team that invests in your success. Pediatrix is seeking a Neonatal Nurse Practitioner (NNP) to join our collaborative and highly respected neonatal team in Kansas City, Missouri. Whether you're an experienced NNP or a new graduate looking for exceptional mentorship and development opportunities, you'll find a supportive environment where you c...

General Nurse Practitioner
Columbia, Missouri
Pediatrix & Obstetrix
Full-time
Permanent
In-person

Live and Work in this midwest college town with small city charm Join our expanding practice at Boone Hospital Center in Columbia, MO, to work as an NNP in our 22-bed, state-of-the-art, Level-III NICU. • Provide clinical care in the NICU and attendance at some deliveries • The schedule includes a combination of 12 or 24 hour shifts • Practice strives to incorporate current best practices and evidence-based medicine into their care • Group participates in the Vermont Oxford Network • Practice offers a robust multi-disciplinary QI program...

General Nurse Practitioner
Farmington, Missouri
TeamHealth Parkland Health Center - Farmington
Full-time
Permanent
In-person

TeamHealth is seeking an advanced practice clinician for interventional pain management services at Parkland Health Center. If you are a nurse practitioner or physician assistant who is passionate about providing excellent patient care, this may be the perfect opportunity for you! This role provides excellent work/life balance with flexible scheduling.  In this role, you will work closely with the pain management physician focused on basic injections with minimum medication management. Prior experience in the field of pain management an...

General Nurse Practitioner
Springfield, Missouri
Curare Physician Recruiting
Full-time
Permanent
In-person

A respected independent health system in the scenic Ozark Mountain region of Northwest Arkansas is seeking a BE/BC Nurse Practitioner or Physician Assistant with experience in Rheumatology to join a growing specialty program serving a large multi-county referral base. Hospital Employee . Competitive Annual Salary. WRVU production incentives. Loan Forgiveness available. Signing Bonus available, contact us for details. Relocation Bonus available. CME time and money available. 401K. Medical/Dental/Vision Plans, Hospital-paid Life/LTD/AD&a...

General Nurse Practitioner
Springfield, Missouri
Curare Physician Recruiting
Full-time
Permanent
In-person

A respected independent health system in the scenic Ozark Mountain region of Northwest Arkansas is seeking a BE/BC Nurse Practitioner or Physician Assistant with experience in Rheumatology to join a growing specialty program serving a large multi-county referral base. Hospital Employee . Competitive Annual Salary. WRVU production incentives. Loan Forgiveness available. Signing Bonus available, contact us for details. Relocation Bonus available. CME time and money available. 401K. Medical/Dental/Vision Plans, Hospital-paid Life/LTD/AD&a...

General Nurse Practitioner
St. Louis, Missouri
TeamHealth CHRISTIAN HOSPITAL PAIN MANAGEMENT CENTER
Full-time
Permanent
In-person

TeamHealth is seeking an advanced practice clinician for interventional pain management services at Christian Hospital. If you are a nurse practitioner or physician assistant who is passionate about providing excellent patient care, this may be the perfect opportunity for you! This role provides excellent work/life balance with Fridays off! In this role, you will work closely with the pain management physician focused on basic injections and ultrasound guided procedures with minimum medication management. Enjoy a positive work environmen...

General Nurse Practitioner
Kansas City, Missouri
Research Medical Center
Full-time
Permanent
In-person

Description Specialization: Neurosurgery Job Summary: Research Medical Center is assisting Midwest Neurosurgery Associates in recruiting an advanced practice provider in Kansas City, Missouri. Qualified Candidates: • ICU or Neuro ICU experience required • Position is full time with flexible 12 hour shifts • This position does not include first assist responsibilities • Ability to obtain both Missouri and Kansas licensure Incentive/Benefits Package: • Competitive salary commensurate with experience • Comprehensive benefits pac...

General Nurse Practitioner
Kansas City, Missouri
HCA Healthcare
Part-time
Permanent
In-person

Description Specialization: Urgent Care Urgent Care Emergency Medicine Urgent Care Family Medicine Urgent Care Internal Medicine Pediatrics Job Summary: CareNow Urgent Care is seeking a board-certified Part-Time Nurse Practitioner to join our Kansas City Market. Qualified Candidates: • Comfortable seeing ages three months and up • Board certified • Has or willing to obtain Kansas and Missouri state medical licensure • Ability to perform first reads on x-rays • Skills to perform patient treatment procedures for most acute illnesse...

General Nurse Practitioner
Kansas City, Missouri
HCA Healthcare
Full-time
Permanent
In-person

Description Specialization: Urgent Care Urgent Care Emergency Medicine Urgent Care Family Medicine Urgent Care Internal Medicine Pediatrics Job Summary: CareNow Urgent Care is seeking a board-certified Full-Time Nurse Practitioner to join our Kansas City Market, specifically providing coverage out of our Lee's Summit clinic location. Qualified Candidates: • Comfortable seeing ages three months and up • Board certified • Has or willing to obtain Kansas and Missouri state medical licensure • Ability to perform first reads on x-rays...

General Nurse Practitioner
Blue Springs, Missouri
Curare Physician Recruiting
Full-time
Permanent
In-person

Advanced Practitioner Hospitalist position available in Kansas City. The Nurse Practitioner focuses on providing general care to patients of all ages, with utmost patience, care, compassion and understanding. Perform tasks within their scope of practice which may include conducting tests, recording medical histories, providing treatments, assisting physicians and enhancing public awareness on the importance of health, and prescribing medications. Full-time employed opportunity. 7 on / 7 off position. Option for days or nights (you cho...

General Nurse Practitioner
Poplar Bluff, Missouri
Poplar Bluff Regional Medical Center
Full-time
Permanent
In-person

Poplar Bluff Regional Medical Center is seeking a dedicated Nurse Practitioner to join our growing Orthopedic Surgery team. This is an excellent opportunity for both experienced providers and new graduates looking to build a rewarding career in a supportive, hospital-employed practice. Position Highlights • Hospital-employed position with a stable, collaborative team • Blend of inpatient and outpatient responsibilities • No operating room time required • Monday–Friday schedule designed to support work-life balance • I...

General Nurse Practitioner
Jefferson City, Missouri
Curare Physician Recruiting
Full-time
Permanent
In-person

NP position at a state-of-the-art facility. Position centrally located between St. Louis and Kansas City! Nestled near the Lake of the Ozarks surrounded by trails, award winning wineries, rivers and lakes! The facility is offering high Sign-on Bonus, Productivity bonus and very lucrative salary! Monday-Thursday. No weekends. Physician owned and operated. Full benefits, 401k plus match. Lucrative salary plus productivity bonus. ...

General Nurse Practitioner
Jefferson City, Missouri
Curare Physician Recruiting
Full-time
Permanent
In-person

NP Hospitalist position at a state-of-the-art facility. Position centrally located between St. Louis and Kansas City! Nestled near the Lake of the Ozarks surrounded by trails, award winning wineries, rivers and lakes! The facility is offering high Sign-on Bonus, Productivity bonus and very lucrative salary! Must have two years experience. Base Salary plus productivity paid on quarterly basis. 7on 7 off or 3on 3off. Full Benefits, 56 hours paid holiday leave, annual CME, and more. Physician owned and operated. ...

Living and Working in Missouri

Key information for nurse practitioners considering jobs in Missouri.

Cost of living
91 / 100

About 9% below the national average.

Source: BEA | Data as of: 9/28/2026

Median home value
$230,300

Well below the U.S. median.

Source: Census ACS | Data as of: 9/28/2026

Property tax
~0.8%

Around the national average. About $1,948/yr on a median home.

Source: Census ACS | Data as of: 9/28/2026

State income tax
4.7% Top rate

Missouri has a 4.7% top marginal state income tax rate. Local income or wage taxes may apply in some jurisdictions.

Source: Missouri Department of Revenue | Data as of: 9/29/2026

Health Professional Shortage Designations in Missouri
  • Primary Care:

    21 counties (18%) have countywide shortage designations. 90 counties (78%) have other HPSA designations that apply to part of a county or to specific underserved populations.

  • Mental Health:

    18 counties (16%) have countywide shortage designations. 95 counties (83%) have other HPSA designations that apply to part of a county or to specific underserved populations.

  • Dental Health:

    21 counties (18%) have countywide shortage designations. 90 counties (78%) have other HPSA designations that apply to part of a county or to specific underserved populations.

  • Eligible healthcare professionals at NHSC-approved sites may qualify for NHSC loan repayment. Eligibility varies by profession, specialty, HPSA type, and program requirements.
  • HPSA status may vary by practice location. Verify a specific practice address with HRSA.

Source: HRSA | Data as of: 9/28/2026

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