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Nurse Practitioner Jobs in South Dakota
Showing 10 nurse practitioner opportunities in South Dakota
PRN Neurosurgery Nurse Practitioner or Physician Assistant - Willing to Train (Rapid City, SD)
General Nurse Practitioner
Rapid City, South Dakota
AAS Healthcare Staffing
Full-time
Permanent
In-person
We’re looking for a dedicated Nurse Practitioner or Physician Assistant to join our expanding Neurosurgery team in Rapid City, SD. This role is a great fit for experienced APPs as well as new graduates or early-career clinicians - comprehensive training is available for candidates who bring a strong clinical foundation and a passion for surgical care. What you’ll do • Round on inpatients, evaluate consults, and manage post-operative follow-ups under neurosurgeon supervision. • First-assist in the operating room for neurosurgical procedur...
Orthopedic Trauma Nurse Practitioner or Physician Assistant (Full-Time) - Rapid City, SD
General Nurse Practitioner
Rapid City, South Dakota
AAS Healthcare Staffing
Full-time
Permanent
In-person
Join a high-performing orthopedic trauma team at a busy regional trauma center serving western South Dakota and surrounding communities. This full-time opportunity is ideal for a Nurse Practitioner or Physician Assistant who wants to practice in a high-acuity, fast-paced environment focused exclusively on orthopedic trauma and emergency care. You’ll collaborate with experienced orthopedic trauma surgeons and gain meaningful operative, inpatient, emergency department, and clinic experience. Position highlights • Trauma- and emergency-base...
Urgent Care Nurse Practitioner / Physician Assistant opening in Rapid City, SD
General Nurse Practitioner
Rapid City, South Dakota
Archway Physician Recruitment
Full-time
Permanent
In-person
Urgent Care Nurse Practitioner / Physician Assistant opening in Rapid City, SD Full-Time | Urgent Care | Varied Hours | No Call An urgent care clinic in Rapid City, South Dakota is seeking a Nurse Practitioner or Physician Assistant to provide outpatient urgent care services in a collaborative, physician-supervised setting. Opportunity Highlights: - Full-time Urgent Care APP role - Predominantly outpatient urgent care setting - Clinic provides patient access 364 days per year - Assess, diagnose, treat, and manage urgent care patients - M...
OB/GYN Nurse Practitioner / Physician Assistant opening in Rapid City, SD
General Nurse Practitioner
Rapid City, South Dakota
Archway Physician Recruitment
Full-time
Permanent
In-person
OB/GYN Nurse Practitioner / Physician Assistant opening in Rapid City, SD Full-Time | Predominantly Outpatient | OB/GYN | 40 Hours An OB/GYN practice in Rapid City, South Dakota is seeking a Nurse Practitioner or Physician Assistant to provide women’s health care in a physician-supervised clinical setting. Opportunity Highlights: - Full-time OB/GYN APP role - Predominantly outpatient practice - Inpatient responsibilities are expected to be 20% or less - Assess, diagnose, treat, and manage OB/GYN patients - Manage selected at-risk or comp...
Inpatient Gastroenterology Nurse Practitioner / Physician Assistant opening in Rapid City, SD
General Nurse Practitioner
Rapid City, South Dakota
Archway Physician Recruitment
Full-time
Permanent
In-person
Inpatient Gastroenterology Nurse Practitioner / Physician Assistant opening in Rapid City, SD Full-Time | Inpatient Gastroenterology | 40 Hours | No OR Requirement A hospital-based Gastroenterology service in Rapid City, South Dakota is seeking a Nurse Practitioner or Physician Assistant to provide inpatient GI care in a physician-supervised setting. Opportunity Highlights: - Full-time Gastroenterology APP role - Inpatient practice setting - Assess, diagnose, treat, and manage gastroenterology patients - Manage selected at-risk or comple...
Cardiac Surgery Nurse Practitioner / Physician Assistant opening in Rapid City, SD
General Nurse Practitioner
Rapid City, South Dakota
Archway Physician Recruitment
Full-time
Permanent
In-person
Cardiac Surgery Nurse Practitioner / Physician Assistant opening in Rapid City, SD Full-Time | Cardiac Surgery | OR, Rounding, Clinic, and Call | 40 Hours An established cardiac surgery practice in Rapid City, South Dakota is seeking a Nurse Practitioner or Physician Assistant to join a growing cardiothoracic and vascular surgery team. Opportunity Highlights: - Full-time Cardiac Surgery APP role - Join a growing team with experienced cardiothoracic and vascular-trained surgeons - Varied schedule includes operating room, rounding, clinic,...
Cardiology Nocturnist Nurse Practitioner / Physician Assistant opening in Rapid City, SD
General Nurse Practitioner
Rapid City, South Dakota
Archway Physician Recruitment
Full-time
Permanent
In-person
Cardiology Nocturnist Nurse Practitioner / Physician Assistant opening in Rapid City, SD Full-Time | Inpatient Cardiology | 14-Hour Overnight Shifts | Nocturnist Role An established cardiology practice in Rapid City, South Dakota is seeking a Nurse Practitioner or Physician Assistant to provide overnight inpatient cardiology coverage. Opportunity Highlights: - Full-time Cardiology Nocturnist APP role - Cover the inpatient cardiology service during overnight shifts - Schedule includes 14-hour overnight shifts - Nocturnal APP team will inc...
Heart Failure Cardiology Nurse Practitioner / Physician Assistant opening in Rapid City, SD
General Nurse Practitioner
Rapid City, South Dakota
Archway Physician Recruitment
Full-time
Permanent
In-person
Heart Failure Cardiology Nurse Practitioner / Physician Assistant opening in Rapid City, SD Full-Time | Cardiology / Heart Failure | Inpatient/Outpatient | 40 Hours A Heart and Vascular program in Rapid City, South Dakota is seeking a Nurse Practitioner or Physician Assistant to support Heart Failure Cardiology care in a blended inpatient and outpatient setting. Opportunity Highlights: - Full-time Heart Failure Cardiology APP role - Blended inpatient and outpatient practice - Assess, diagnose, treat, and manage cardiology and heart failu...
Locum Tenens NP - Emergency Medicine Job in SD WBY# JOB-3340695
General Nurse Practitioner
De Smet, South Dakota
Weatherby Healthcare
Full-time
Locum Tenens
In-person
$75-$121 per hour
Weatherby can help you build a custom career plan, with multiple positions available for you today. Call us for specific details on your future job today. • Friday 8 am - Monday 8 am shift -- 72-hour weekend coverage • ED averages 2 - 3 visits per day • Inpatient averages less than 1 patient per day • Hospital setting • ATLS and ACLS certifications required • Hospital privileges required • Health, vision, dental, and 401(k) retirement benefits offered • Competitive compensation • Paid malpractice insurance • 24-hour access to your Weathe...
Nurse Practitioner Job in South Dakota
General Nurse Practitioner
Sioux Falls, South Dakota
Curare Physician Recruiting
Full-time
Permanent
In-person
Established clinic in eastern South Dakota is seeking a Nurse Practitioner or Physician Assistant to join their practice. Group consists of 1 MD and 2 APP's. Traditional outpatient clinic with inpatient rounding duties including periodic nursing home rounds and ED call. Large, newly remodeled, clinic attached to a 25-Bed critical access hospital. Centrally located, it's easily accessible for those living on the beautiful nearby lakes. Patients come from over 30 miles in any direction for car Single Specialty Group Employee . Annual Salar...
Living and Working in South Dakota
Key information for nurse practitioners considering jobs in South Dakota.
Cost of living
89 / 100
About 11% below the national average.
Source: BEA | Data as of: 9/28/2026
Median home value
$257,400
Well below the U.S. median.
Source: Census ACS | Data as of: 9/28/2026
Property tax
~1.1%
Around the national average. About $2,724/yr on a median home.
Source: Census ACS | Data as of: 9/28/2026
State income tax
None
South Dakota has no state individual income tax.
Source: South Dakota Department of Revenue | Data as of: 9/29/2026
Health Professional Shortage Designations in South Dakota
Primary Care:
30 counties (45%) have countywide shortage designations. 19 counties (29%) have other HPSA designations that apply to part of a county or to specific underserved populations.
Mental Health:
62 counties (94%) have countywide shortage designations. 4 counties (6%) have other HPSA designations that apply to part of a county or to specific underserved populations.
Dental Health:
20 counties (30%) have countywide shortage designations. 20 counties (30%) have other HPSA designations that apply to part of a county or to specific underserved populations.
- Eligible healthcare professionals at NHSC-approved sites may qualify for NHSC loan repayment. Eligibility varies by profession, specialty, HPSA type, and program requirements.
- HPSA status may vary by practice location. Verify a specific practice address with HRSA.
Source: HRSA | Data as of: 9/28/2026
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